AAV Gene Therapy Manufacturing For Scientists

  • Course Price: $150 USD
  • BIO Member Price: $120 USD
  • Course Run Time: 65 minutes
  • Course Level: Level 2 - General
  • Completion Period: 2 week

AAV Gene Therapy Manufacturing For Scientists uses scientific vocabulary and concepts that require the learner have an excellent command of molecular biology. This class explains the features, functions, and design of four AAV viral vector platforms, followed by an in-depth explanation of the upstream and downstream AAV manufacturing process. The class reviews the CMC regulatory component of AAV manufacturing, highlighting the analytical and comparability of manufacturing platforms. A quick review of the AAV manufacturing facility and the workflows round out this course.

Suggested Prerequisites

Biomanufacturing

Takeaways
  1. Description of the structures and functions of the AAV viral vector and how this influences tropism.
  2. Listing of the AAVs serotypes and how new serotype genomes are designed.
  3. Compare and contrast four primary AAV vector platforms, including their precursor materials, critical raw materials, and CMC considerations.
  4. Explanation of how each of the following is characterized concerning viral vectors: safety, identity, potency, quality, and purity.
  5. Discussion of key regulatory considerations for AAV manufacturing.
Certificate Requirements
  • View entire course
  • Pass course exam with a 70 percent
Download Agenda
Certificate Requirements
  • View entire course
  • Pass course exam with a 70 percent
Trailer
Section 1: AAV Overview
Provides an overview of the properties of the naturally occurring Adeno-associated virus including its origin and characteristics.
Section 2: AAV Vectors
Describes how the adeno-associated virus is utilized as an AAV vector. Includes a discussion of the general characteristics and composition of AAV vir...More
Section 3: AAV Manufacturing and Control
Discusses AAV Manufacturing and control including an introduction to manufacturing, the four primary platforms for AAV production, the characterizatio...More
Final Quiz
Certificate Requirements
  • View entire course
  • Pass course exam with a 70 percent